Mechanism of action of beta-lactam antibiotics at the molecular level

Rapid and easy development of versatile tools to study protein/ligand interactions.

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Competitive inhibitors of the CphA metallo-beta-lactamase from Aeromonas hydrophila.

Antimicrobial agents and chemotherapy·2007

Molecular characterisation of a versatile peroxidase from a Bjerkandera strain.

Journal of biotechnology·2005

Role of Cys221 and Asn116 in the zinc-binding sites of the Aeromonas hydrophila metallo-beta-lactamase.

Cellular and molecular life sciences : CMLS·2003

Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril.

Journal of molecular biology·2003

Crystallographic analysis of family 11 endo-beta-1,4-xylanase Xyl1 from Streptomyces sp. S38.

Acta crystallographica. Section D, Biological crystallography·2001

Genistein targets Wnt5a to alleviate temporomandibular joint osteoarthritis by suppressing JNK/JUN-dependent MMP9 activation.

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Biochemical pharmacology·2026

Metabolism-mediated herb-drug interaction between milk thistle and resmetirom in MCD diet-induced metabolic dysfunction-associated steatohepatitis rat model.

Biochemical pharmacology·2026

Citicoline in cardiovascular protection: mechanistic roles of choline and acetylcholine.

Biochemical pharmacology·2026

Monocarboxylate transporters 1 and 4 in tumor lactate exchange: Molecular mechanisms, pharmacological inhibition, and therapeutic translation.

Biochemical pharmacology·2026

Overcoming drug delivery barriers to Unlock the therapeutic potential of conventional chemotherapy in glioblastoma.

Biochemical pharmacology·2026

Lipid Extract from Ulva ohnoi Algae: Chemical Characterization, Antibacterial Potential, and Cytotoxicity in the Search for New Agents Against MDR Infections.

Marine biotechnology (New York, N.Y.)·2026

Fungi are overlooked dimethylsulfoniopropionate degraders in marine environments.

The ISME journal·2026

Single-Cell Detection and Quantification of Metabolically Active Bacteria in Soil Using Heavy-Water Labeling and Raman Microspectroscopy.

Journal of visualized experiments : JoVE·2026

Testing the safety of nature-based microbial exposure in atopic dermatitis patients: a randomized, placebo-controlled, double-blinded pilot trial.

European journal of dermatology : EJD·2026

Evaluation of the Antifungal Activity of Metabolites Produced by Soil Actinomycetes on the Candida Species Isolated from Candidemia.

Advanced biomedical research·2026

Age‑Related Remodeling of the Skin Microbiome in Healthy Women: Site‑Specific Patterns Between Sebaceous and Dry Skin Regions.

Clinical, cosmetic and investigational dermatology·2026

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Mechanism of action of beta-lactam antibiotics at the molecular level

Related Concept Videos

Rapid and easy development of versatile tools to study protein/ligand interactions.

Competitive inhibitors of the CphA metallo-beta-lactamase from Aeromonas hydrophila.

Molecular characterisation of a versatile peroxidase from a Bjerkandera strain.

Role of Cys221 and Asn116 in the zinc-binding sites of the Aeromonas hydrophila metallo-beta-lactamase.

Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril.

Crystallographic analysis of family 11 endo-beta-1,4-xylanase Xyl1 from Streptomyces sp. S38.

Genistein targets Wnt5a to alleviate temporomandibular joint osteoarthritis by suppressing JNK/JUN-dependent MMP9 activation.

Context-dependent protective and pathogenic functions of YTHDF1 in MASLD and hepatocellular carcinoma: Mechanisms and design of therapeutics.

Metabolism-mediated herb-drug interaction between milk thistle and resmetirom in MCD diet-induced metabolic dysfunction-associated steatohepatitis rat model.

Citicoline in cardiovascular protection: mechanistic roles of choline and acetylcholine.

Monocarboxylate transporters 1 and 4 in tumor lactate exchange: Molecular mechanisms, pharmacological inhibition, and therapeutic translation.

Overcoming drug delivery barriers to Unlock the therapeutic potential of conventional chemotherapy in glioblastoma.

Lipid Extract from Ulva ohnoi Algae: Chemical Characterization, Antibacterial Potential, and Cytotoxicity in the Search for New Agents Against MDR Infections.

Fungi are overlooked dimethylsulfoniopropionate degraders in marine environments.

Single-Cell Detection and Quantification of Metabolically Active Bacteria in Soil Using Heavy-Water Labeling and Raman Microspectroscopy.

Testing the safety of nature-based microbial exposure in atopic dermatitis patients: a randomized, placebo-controlled, double-blinded pilot trial.

Evaluation of the Antifungal Activity of Metabolites Produced by Soil Actinomycetes on the Candida Species Isolated from Candidemia.

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Mechanism of action of beta-lactam antibiotics at the molecular level

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