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Related Experiment Video

Updated: Nov 10, 2025

Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry
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Exhaled breath biomarker sensing.

Alina Vasilescu1, Borys Hrinczenko2, Greg M Swain3

  • 1International Centre of Biodynamics, Bucharest, Romania.

Biosensors & Bioelectronics
|April 2, 2021
PubMed
Summary
This summary is machine-generated.

Exhaled breath analysis detects respiratory diseases by measuring chemical markers. This review covers mass spectrometry and biosensors for analyzing exhaled breath (EB) and exhaled breath condensate (EBC).

Keywords:
BiomarkersBiosensorsChemical sensorsExhaled breath condensate

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Last Updated: Nov 10, 2025

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Area of Science:

  • * Scientific research focused on analyzing exhaled breath for disease detection.
  • * Explores the potential of exhaled breath analysis in diagnosing respiratory conditions.

Background:

  • * Respiratory diseases can alter physiological chemical markers.
  • * Detecting these abnormal markers in breath is a key research area.

Purpose of the Study:

  • * To introduce exhaled breath analysis for detecting respiratory diseases.
  • * To review sensing methods for physiological markers in exhaled breath.

Main Methods:

  • * Review of mass spectrometry techniques.
  • * Detailed discussion of biosensor applications for exhaled breath (EB) and exhaled breath condensate (EBC) analysis.

Main Results:

  • * Identified mass spectrometry and biosensors as primary sensing methods.
  • * Highlighted biosensor applications in EB and EBC analysis.

Conclusions:

  • * Exhaled breath analysis shows promise for respiratory disease detection.
  • * Recommendations for future development in EBC biomarker sensing.