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Updates on Laboratory Evaluation of Feline Cardiac Diseases
Alessandra Gavazza1, Andrea Marchegiani1, Lorenza Guerriero2
1School of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione 93/95, 62024 Matelica, Italy.
Insights
This study reviews feline clinical pathology for heart diseases. It highlights how traditional tests and specific biomarkers like Troponin and Natriuretic Peptides aid in diagnosing and monitoring cardiac conditions in cats, including those with thyroid issues.
Area of Science:
- Veterinary Medicine
- Cardiology
- Clinical Pathology
Background:
- Cardiovascular diseases in cats can alter standard laboratory tests.
- Specific biomarkers offer greater insight into myocardial damage than traditional tests.
- Concurrent cardiovascular and thyroid diseases are common in cats.
Purpose of the Study:
- To provide a comprehensive literature review on feline clinical pathology related to heart diseases.
- To categorize alterations in traditional laboratory tests and biomarkers for feline cardiac conditions.
- To emphasize the importance of thyroid profiling in cats with heart disease.
Main Methods:
- Literature review of existing studies on feline cardiovascular disease and clinical pathology.
- Analysis and categorization of traditional laboratory tests (e.g., blood count, biochemistry, coagulation).
- Evaluation of specific cardiac biomarkers (e.g., Troponin, Natriuretic Peptides) and thyroid profiles.
Main Results:
- Traditional laboratory tests are useful but lack specificity for feline heart disease.
- Cardiac biomarkers like Troponin and Natriuretic Peptides provide crucial data on myocardial damage.
- Thyroid function evaluation is essential due to the high prevalence of hyperthyroidism in cats with cardiac disease.
Conclusions:
- A structured approach to laboratory diagnostics, including specific biomarkers, is vital for feline cardiac disease management.
- Understanding alterations in both traditional tests and advanced biomarkers improves diagnostic accuracy.
- Integrated assessment of cardiac and thyroid health is critical for effective feline cardiology practice.
Abstract:
Laboratory tests can be altered in cardiovascular diseases and the investigation of specific tests or biomarkers may provide additional information about myocardial damage. Traditional laboratory tests, such as cell blood count, serum biochemistry, and coagulation, can be useful in investigating patients, but are not specific. However, markers like Troponin and Natriuretic Peptides may possibly furnish further data on myocardium damage and can be used in both studying and monitoring cats with cardiac disease. Moreover, the evaluation of the thyroid profile is very important as hyperthyroid cats concomitant cardiovascular diseases are very common and they can also be a direct consequence of endocrinopathy. The purpose of this manuscript is to provide the widest possible overview of what is present in the literature about the feline clinical pathology of heart diseases through a rational division of the main alterations of traditional tests and biomarkers.
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