Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Depression through the ages.

T Sunderland1

  • 1National Institute of Mental Health, Bethesda, MD 20892.

Neurobiology of Aging
|January 1, 1988
PubMed
Summary
This summary is machine-generated.

This review highlights the complex biological modeling of depression, especially its connection to aging. It serves as a valuable starting point for understanding this challenging research area.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Five challenges to reconcile agricultural land use and forest ecosystem services in Southeast Asia.

Conservation biology : the journal of the Society for Conservation Biology·2016
Same author

Power, policy and the Prunus africana bark trade, 1972-2015.

Journal of ethnopharmacology·2015
Same author

Pharmacology of human memory and cognition: illustrations from the effects of benzodiazepines and cholinergic drugs.

Journal of psychopharmacology (Oxford, England)·2012
Same author

The effects of thyrotropin-releasing hormone and scopolamine in Alzheimer's disease and normal volunteers.

Journal of psychopharmacology (Oxford, England)·2012
Same author

Fine-needle, negative-pressure lumbar puncture: a safe technique for collecting CSF.

Neurology·2002
Same author

Working memory and apolipoprotein E: what's the connection?

Neuropsychologia·2002
Same journal

Amygdala and hippocampal volumes as neural correlates of resilience and loneliness in older adults.

Neurobiology of aging·2026
Same journal

Hippocampal-cortical structural networks in the progression of cognitive impairment: A source-based morphometry analysis in individuals with subjective cognitive decline, mild cognitive impairment and Alzheimer's disease.

Neurobiology of aging·2026
Same journal

Brain structure in the cingulate cortex and locus coeruleus in late life is associated with engagement in complex mental activities across the life span.

Neurobiology of aging·2026
Same journal

Age-related differences in motor learning, sensorimotor neurochemistry, and cortical reactivity co-occur but are dissociated.

Neurobiology of aging·2026
Same journal

How cognition and hearing-related measures covary with hippocampal subfield features from structural MRI in younger and older adults.

Neurobiology of aging·2026
Same journal

Decreased awareness of cognitive decline is associated with multimodal Alzheimer's disease biomarkers in cognitively unimpaired individuals.

Neurobiology of aging·2026
See all related articles

Area of Science:

  • Neuroscience
  • Psychiatry
  • Computational Biology

Background:

  • Biological modeling offers insights into complex conditions like depression.
  • The relationship between aging and depression remains largely uncharted.
  • Previous research has faced challenges in establishing definitive conclusions.

Purpose of the Study:

  • To review the current state of biological modeling in depression research.
  • To highlight the complexities and controversies within the field.
  • To provide a foundational resource for students and researchers.

Main Methods:

  • Literature review of existing studies on biological modeling in depression.
  • Analysis of the multifaceted relationship between aging and depression.

Related Experiment Videos

  • Synthesis of controversial findings and areas requiring further investigation.
  • Main Results:

    • The authors commend the comprehensive review of biological modeling in depression.
    • The review underscores the difficulty in drawing definitive conclusions.
    • The multifaceted link between aging and depression is identified as a key area for future study.

    Conclusions:

    • The reviewed work is a substantial achievement in a controversial field.
    • The review is an essential starting point for those studying depression and aging.
    • Further research is needed to fully understand the biological underpinnings of depression, particularly in aging populations.