Related Experiment Video
Updated: Nov 10, 2025

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
Diagnostic Process Using Endoscopy for Biliary Strictures: A Narrative Review
Yuki Tanisaka1, Masafumi Mizuide1, Akashi Fujita1
1Department of Gastroenterology, Saitama Medical University International Medical Center, 1397-1, Yamane, Hidaka, Saitama 350-1298, Japan.
Diagnosing indeterminate biliary strictures can be difficult. This review explores advanced endoscopic techniques, beyond traditional methods like ERCP, for improved accuracy in identifying benign or malignant lesions.
Area of Science:
- Gastroenterology
- Diagnostic Imaging
- Endoscopy
Background:
- Biliary strictures present a diagnostic challenge with a differential including benign and malignant lesions.
- Accurate diagnosis requires integrating clinical, laboratory, and imaging data, with endoscopy playing a crucial role.
Purpose of the Study:
- To review and discuss the diagnostic process for indeterminate biliary strictures.
- To highlight the evolving role of endoscopic modalities in achieving accurate diagnosis.
Main Methods:
- Review of current literature on diagnostic approaches for biliary strictures.
- Focus on the utility of various endoscopic techniques, including peroral cholangioscopy, confocal laser endomicroscopy, and endoscopic ultrasound (EUS).
Main Results:
- While imaging and endoscopic retrograde cholangiopancreatography (ERCP) are standard, ERCP has limitations in intraluminal visualization.
- Emerging endoscopic tools like EUS and peroral cholangioscopy offer improved diagnostic capabilities for indeterminate biliary strictures.
Conclusions:
- Selection of appropriate endoscopic modalities depends on patient condition, lesion characteristics, and endoscopist expertise.
- Advanced endoscopic techniques are vital for improving the accuracy of diagnosing indeterminate biliary strictures.
Related Concept Videos
Endoscopic Procedures V: ERCP
Patient...
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Endoscopic Procedures I: Esophagogastroduodenoscopy
During an EGD, the endoscope can be used to:
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Endoscopic Studies I: Bronchoscopy and Thoracoscopy
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
Endoscopic Procedures II: Colonoscopy

