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Updated: Nov 10, 2025

The Use of Reverse Phase Protein Arrays RPPA to Explore Protein Expression Variation within Individual Renal Cell Cancers
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Published on: January 22, 2013

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Leptin Is Associated with Poor Clinical Outcomes and Promotes Clear Cell Renal Cell Carcinoma Progression

Wen-Lang Fan1, Yuan-Ming Yeh1, Tsung-Ta Liu2

  • 1Genomic Medicine Core Laboratory, Chang Gung Memorial Hospital, Linkou 33305, Taiwan.

Biomolecules
|April 3, 2021
PubMed
Summary

Leptin promotes renal cell carcinoma (RCC) cell migration and is linked to poor patient outcomes. This study reveals leptin activates the planar cell polarity/JNK signaling pathway, driving cancer progression.

Keywords:
clinical outcomeleptinrenal cell carcinoma

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