Related Experiment Video
Updated: Nov 10, 2025

06:11
Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring
Published on: May 17, 2024
891
Associations between Disability and Infertility among U.S. Reproductive-Aged Women
1Department of Public Health, School of Social Sciences, Humanities and Arts, Health Science Research Institute, University of California, Merced, CA 95343, USA.
Summary
Women with disabilities have higher odds of infertility and may be less likely to seek infertility care. This highlights the need for equitable reproductive health policies and practices for women with disabilities.
Area of Science:
- Reproductive Health
- Disability Studies
- Public Health
Background:
- Disability is a significant factor influencing health outcomes.
- Understanding the intersection of disability and reproductive health is crucial for equitable care.
- Limited research exists on infertility prevalence and care-seeking behaviors among women with disabilities.
Purpose of the Study:
- To investigate the association between self-reported disabilities and infertility.
- To determine if disabilities decrease the likelihood of seeking infertility-related care.
- To identify disparities in reproductive health services for women with disabilities.
Main Methods:
- Cross-sectional analysis of 3789 non-pregnant women aged 18-49 years (NHANES, 2013-2018).
- Self-reported data on disabilities and infertility collected through trained interviewer-administered personal interviews.
- Logistic regression models used to estimate adjusted odds ratios (aOR) and 95% confidence intervals, adjusting for confounders and complex survey design.
Main Results:
- Women with disabilities (WWD) exhibited higher odds of infertility compared to women without disabilities (aOR: 1.78).
- Sensory (aOR: 2.32) and cognitive disabilities (aOR: 1.77) were significantly associated with increased odds of infertility.
- Among women with infertility, WWD showed a trend towards reduced likelihood of seeking infertility-related care (aOR: 0.68), though not statistically significant.
Conclusions:
- Women with disabilities face a higher prevalence of infertility.
- WWD may encounter barriers to accessing essential infertility-related healthcare services.
- There is a critical need for further research and the implementation of equitable policies to address the reproductive health needs of women with disabilities.
Related Concept Videos
Infertility in Females
3.3K
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
Endometriosis, a condition characterized by abnormal growth of...
3.3K
Infertility in Males
389
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
389
Oogenesis
67.4K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
67.4K
Spermatogenesis
107.0K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
107.0K
Nondisjunction
4.4K
Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate correctly and move to the opposite poles of the cells. This produces daughter cells with abnormal chromosome numbers. Nondisjunction is common during anaphase I or anaphase II of meiosis. Mutations in synaptonemal complex proteins that attach homologous chromosomes increase the chances of nondisjunction in anaphase I of meiosis I. In contrast, mutations in topoisomerases and condensins that hold...
4.4K
Nondisjunction
79.2K
During meiosis, chromosomes occasionally separate improperly. This occurs due to failure of homologous chromosome separation during meiosis I or failed sister chromatid separation during meiosis II. In some species, notably plants, nondisjunction can result in an organism with an entire additional set of chromosomes, which is called polyploidy. In humans, nondisjunction can occur during male or female gametogenesis and the resulting gametes possess one too many or one too few chromosomes.
79.2K

