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Updated: Aug 18, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
[Postmenopausal osteoporosis. Early diagnosis as an indication for preventive hormone therapy]
M Dören1, M Montag, H P Schneider
1Klinik und Poliklinik für Geburtshilfe und Frauenheilkunde B, Westfälischen Wilhelms-Universität Münster.
Abstract:
Idiopathic osteoporosis mainly affects postmenopausal women. The normal trabecular volume of the lumbar vertebrae in a sample of healthy perimenopausal women was established by monoenergetic computed tomography. Early diagnosis of diminished bone mass is crucial for the identification of women at risk for involuntary osteoporosis following climacteric estrogen depletion. Body weight, endogenous levels of sex steroids, renal calcium and hydroxyproline excretions are not related to individual bone mass in the lumbar spine.
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