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Rhopressa-induced corneal edema: a case report.

Matthew J Chu1, Michael Song2, Trisa Palmares1

  • 1Southern California Eye Physicians & Surgeons, 800 S. Fairmount Ave., #207, Pasadena, CA, 91105, USA.

Journal of Medical Case Reports
|April 3, 2021
PubMed
Summary
This summary is machine-generated.

Rhopressa (netarsudil) can cause corneal edema, even in patients without prior eye conditions. This case highlights potential unknown side effects of this glaucoma medication.

Keywords:
Corneal edemaGlaucomaNetarsudil (Rhopressa)Rho kinase inhibitors

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Area of Science:

  • Ophthalmology
  • Pharmacology

Background:

  • Rhopressa (netarsudil) is a novel Rho-associated protein kinase (ROCK) inhibitor used for open-angle glaucoma.
  • It effectively lowers intraocular pressure (IOP) but commonly causes conjunctival hyperemia.

Observation:

  • A case of Rhopressa-induced corneal edema is presented in a 79-year-old African-American woman.
  • The patient had no prior history of corneal edema or uveitis, differentiating this case from previous reports.

Findings:

  • Corneal edema developed in a patient treated with Rhopressa for glaucoma.
  • The corneal edema resolved after discontinuation of Rhopressa, suggesting a causal link.

Implications:

  • This case suggests Rhopressa may cause corneal edema in individuals without pre-existing ocular conditions.
  • Further investigation into the ocular side effects of Rhopressa and other ROCK inhibitors is warranted.