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Updated: Nov 10, 2025
Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy
Published on: March 10, 2023
Feasibility of Reductive Hepatectomy in Patients With BCLC B and C Hepatocellular Carcinoma
Yuki Yasuhara1, Shohei Komatsu2, Kaori Kuramitsu1
1Department of Surgery, Division of Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Background/Aim:
Few studies have established a definite conclusion regarding the limitation of surgical treatment for patients with Barcelona Clinic Liver Cancer (BCLC) stage B and C hepatocellular carcinoma (HCC).
Patients And Methods:
A retrospective analysis was performed on 717 consecutive patients who underwent initial hepatectomy for HCC.
Results:
Reductive hepatectomy was performed in 103 patients, with a median survival time (MST) of 18.0 months. Total bilirubin and albumin levels were identified as independent prognostic factors. The predictive score of these factors ranged from 0 to 2. Subsequent local treatment was performed in 91.0, 75.0, and 25.0% of patients who scored 0, 1, and 2, respectively. The MST for patients with a score of 0, 1, and 2 was 20.1, 14.8, and 2.7 months, respectively, with a significant difference.
Conclusion:
Patients with BCLC stage B and C could be properly treated with reductive hepatectomy and subsequent local treatments.
