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Published on: December 7, 2019
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Inflammatory Pseudotumor Resembling a Malignant Pancreatic Disease Process.
Jamie Kaplan1, Catherine Mangum2, Mira Shoukry2
1Department of General Surgery, Mayo Clinic, Jacksonville, FL, U.S.A. Kaplan.jamie@mayo.edu.
Anticancer Research
|April 4, 2021
Summary
This case report highlights a pancreatic inflammatory pseudotumor, a rare condition mimicking malignancy. Diagnosis requires careful consideration of imaging and pathology for this challenging entity.
Area of Science:
- Gastroenterology
- Pathology
- Surgical Oncology
Background:
- Inflammatory pseudotumors present diagnostic challenges due to their varied characteristics.
- They can mimic malignancy clinically, radiographically, and histologically.
Observation:
- A 65-year-old female presented with fever, abdominal pain, and anemia.
- Imaging revealed an ill-defined soft tissue mass between the left adrenal gland and pancreatic tail, suspicious for malignancy.
Findings:
- Diagnostic laparoscopy and subsequent resection were performed.
- Pathology confirmed the mass as a pancreatic inflammatory pseudotumor, characterized by dense fibrosis, spindled cells, and inflammatory infiltrates with a specific immunohistochemical profile.
Implications:
- Pancreatic inflammatory pseudotumor should be considered in the differential diagnosis of patients with nonspecific symptoms and imaging findings of an ill-defined abdominal mass.
- Accurate diagnosis is essential to avoid unnecessary aggressive treatment for potentially benign conditions.
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