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Case Report: Concurrent Clonidine Abuse and Opioid Use Disorder
Brian G Mitchell1,2, Jaekyu Lee1
1Department of Pharmacy Services, Michael E. DeBakey VA Medical Center, Houston, Texas, USA.
Clonidine abuse, often combined with opioids, is an underestimated issue. Healthcare providers must be vigilant when prescribing clonidine alongside opioids due to potential for abuse and withdrawal complications.
Area of Science:
- Pharmacology
- Addiction Medicine
- Geriatric Medicine
Background:
- Clonidine, an alpha-2 adrenergic agonist, is prescribed for hypertension and substance use disorder withdrawal.
- Case reports indicate clonidine abuse, often with opioids, to enhance euphoric effects.
Observation:
- This report details clonidine abuse and withdrawal management in an elderly patient with opioid use disorder.
- The patient's concurrent use of clonidine and opioids highlights a complex clinical scenario.
Findings:
- Clonidine abuse is frequently underestimated by healthcare providers.
- The concurrent prescription of clonidine and opioids necessitates careful monitoring.
Implications:
- Increased vigilance is crucial for healthcare providers managing patients with opioid use disorder.
- The controversial use of clonidine in opioid detoxification requires further investigation.
- Addressing clonidine abuse is essential amidst the ongoing opioid epidemic.
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