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Updated: Nov 10, 2025

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
Unexpected giant cell aortitis in a young patient
Lawrence Nair1, Eshan Senanayake1, Bruce Thomson1
1Department of Cardiothoracic Surgery, The Prince Charles Hospital, Brisbane, Queensland, Australia.
Introduction And Importance:
Giant cell aortitis is a rare cause of ascending aortic aneurysm disease. Patients presenting with aneurysms caused by giant cell aortitis are at high risk of devastating complications.
Case Presentation:
A 35-year-old female with an ascending aortic aneurysm, underwent an aortic root and ascending aorta replacement and subsequently was found to have giant cell aortitis on histopathology.
Discussion And Conclusion:
This case illustrates a very rare cause for aortopathy in a young healthy patient, who may have ruptured or dissected, if not for timely operative intervention.
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