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The prevalence of seizures in children with developmental delay

Raidah Albaradie1, Hafiz Habibullah1, Ali Mir1

  • 1From the Department of Pediatric neurology (Albaradie, Habibullah, Mir), Neuroscience Center (Bashir), King Fahad Specialist Hospital, Dammam, from the College of Medicine (Alshammari, Alajmi, Alsubaie, Alsudairi), Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia.

Neurosciences (Riyadh, Saudi Arabia)
|April 5, 2021
PubMed

Insights

Epilepsy is common in children with global developmental delay (GDD). Advanced paternal age and seizure type are key factors associated with epilepsy in this population.

Area of Science:

  • Pediatric Neurology
  • Developmental Pediatrics
  • Clinical Epidemiology

Background:

  • Global developmental delay (GDD) is a significant concern in pediatric neurology.
  • The co-occurrence of epilepsy in children with GDD requires further investigation.
  • Understanding risk factors for epilepsy in GDD is crucial for early intervention.

Purpose of the Study:

  • To determine the prevalence of epilepsy in children diagnosed with GDD.
  • To identify patient characteristics associated with epilepsy in GDD.
  • To examine the influence of risk factors on the GDD-epilepsy association.

Main Methods:

  • Retrospective cross-sectional study design.
  • Data collected from electronic medical records of 200 pediatric patients with GDD.
  • Study conducted at King Fahad Specialist Hospital, Saudi Arabia.

Main Results:

  • Epilepsy prevalence was 56% among children with GDD.
  • Generalized onset motor seizures were the most common type (37.5%).
  • Advanced paternal age was significantly associated with epilepsy (p=0.003).

Conclusions:

  • High prevalence of epilepsy in children with GDD highlights a critical clinical issue.
  • Advanced paternal age and specific seizure types are significant factors in the GDD-epilepsy correlation.
  • Further research is warranted to explore the complex relationship between GDD and epilepsy.
Abstract

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