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Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental
Jianbo Qu1, Zhi-Hao Zhang1, Haitao Zhang1
1School of Light Industry and Engineering, Qi Lu University of Technology, Shandong Academy of Sciences, Jinan, China.
Abstract:
Diethyl malonate-based fluorescent probe NE-N H was constructed for monitoring hydrazine (N2H4). The novel probe NE-N H exhibits good properties, such as large Stokes shift (about 125 nm), good selectivity, and low cytotoxicity. This sensing probe NE-N H can be operated to detect hydrazine in living HeLa cells. Especially after soaking in probe solution, the thin-layer chromatography (TLC) plate could detect the vapor of hydrazine. Therefore, the probe NE-N H might be used to monitor hydrazine in biosamples and environmental problem.
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