Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioremediation00:46

Bioremediation

21.6K
Bioremediation is the use of prokaryotes, fungi, or plants to remove pollutants from the environment. This process has been used to remove harmful toxins in groundwater as a byproduct of agricultural run-off and also to clean up oil spills.
21.6K
Microbial Fermentation01:23

Microbial Fermentation

831
Fermentation is a crucial anaerobic metabolic process that enables microbes to derive energy from sugar without relying on oxygen or an electron transport chain. This process is fundamental to various biological and industrial applications and is classified based on the metabolic products generated.Role of Pyruvate in FermentationPyruvate and its derivatives serve as key electron acceptors in fermentative pathways. The oxidation of NADH to regenerate NAD+ is essential for the continuation of...
831

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Emerging governance considerations for the deployment of genetically engineered microbes.

Current opinion in microbiology·2025
Same author

One Health for all: Implementing international frameworks with local communities.

PLOS global public health·2025
Same author

Harnessing plant agriculture to mitigate climate change: A framework to evaluate synthetic biology (and other) interventions.

Plant physiology·2025
Same author

Characterization of Fluorescent Reporters for Flow Cytometry-Based Single-Cell Studies in <i>Saccharomyces cerevisiae</i>.

ACS synthetic biology·2025
Same author

Iron-Sulfur Cluster Enzymes of the Methylerythritol Phosphate Pathway: IspG and IspH.

Biochemistry·2025
Same author

The methylerythritol phosphate pathway as an oxidative stress sense and response system.

Nature communications·2024
Same journal

A CURE for synthetic regulation of gene expression: rapid screening of guide RNA efficacy as a framework for enabling undergraduate research in plant synthetic biology.

Synthetic biology (Oxford, England)·2026
Same journal

Chemically synthesized high-fidelity oligos ≤ 600 nt as building blocks to accelerate complex gene construction in synthetic biology.

Synthetic biology (Oxford, England)·2026
Same journal

Off-target detection of CRISPR-Cas9 nuclease <i>in vitro</i> with CROFT-Seq.

Synthetic biology (Oxford, England)·2026
Same journal

Going beyond size: exploring the metabolic burden in <i>Pseudomonas putida</i> during heterologous protein production.

Synthetic biology (Oxford, England)·2026
Same journal

A protein-fragment complementation assay to quantify synthetic protein scaffold efficiency.

Synthetic biology (Oxford, England)·2026
Same journal

EASY-C: Extraction and Analysis of Small Yeast Chromosomes-A rapid and universal platform for recovering artificial mini-chromosomes from synthetic Sc2.0 yeast and large plasmids from <i>Saccharomyces cerevisiae</i> and nonconventional yeast species.

Synthetic biology (Oxford, England)·2026
See all related articles

Related Experiment Video

Updated: Nov 10, 2025

Installation of the Big Box Biochar Kiln for Biochar Production
02:58

Installation of the Big Box Biochar Kiln for Biochar Production

Published on: October 27, 2023

3.2K

Building a biofoundry.

Maciej B Holowko1, Emma K Frow2, Janet C Reid1

  • 1CSIRO Synthetic Biology Future Science Platform, CSIRO Land and Water, Brisbane, QLD 4102, Australia.

Synthetic Biology (Oxford, England)
|April 5, 2021
PubMed
Summary
This summary is machine-generated.

Establishing a biofoundry requires careful planning of operational and financial models. Addressing key considerations ensures the long-term sustainability and success of high-throughput biological engineering infrastructure.

Keywords:
biofoundryhigh-throughputsynthetic biology

More Related Videos

Ecosystem Fabrication EcoFAB Protocols for The Construction of Laboratory Ecosystems Designed to Study Plant-microbe Interactions
11:57

Ecosystem Fabrication EcoFAB Protocols for The Construction of Laboratory Ecosystems Designed to Study Plant-microbe Interactions

Published on: April 10, 2018

18.9K
Author Spotlight: Developing Synthetic Microbial Communities for Generating Second-Generation Biofertilizers
04:29

Author Spotlight: Developing Synthetic Microbial Communities for Generating Second-Generation Biofertilizers

Published on: May 24, 2024

1.3K

Related Experiment Videos

Last Updated: Nov 10, 2025

Installation of the Big Box Biochar Kiln for Biochar Production
02:58

Installation of the Big Box Biochar Kiln for Biochar Production

Published on: October 27, 2023

3.2K
Ecosystem Fabrication EcoFAB Protocols for The Construction of Laboratory Ecosystems Designed to Study Plant-microbe Interactions
11:57

Ecosystem Fabrication EcoFAB Protocols for The Construction of Laboratory Ecosystems Designed to Study Plant-microbe Interactions

Published on: April 10, 2018

18.9K
Author Spotlight: Developing Synthetic Microbial Communities for Generating Second-Generation Biofertilizers
04:29

Author Spotlight: Developing Synthetic Microbial Communities for Generating Second-Generation Biofertilizers

Published on: May 24, 2024

1.3K

Area of Science:

  • Synthetic biology
  • Bioengineering
  • High-throughput experimentation

Background:

  • Biofoundries offer automated infrastructure for biological systems engineering.
  • They enable high-throughput synthetic biology, expanding research possibilities.
  • Establishing biofoundries presents significant technical and operational challenges.

Purpose of the Study:

  • To outline critical considerations for establishing and operating biofoundries.
  • To provide guidance for sustainable biofoundry ventures.
  • To facilitate the integration of advanced technology and community engagement.

Main Methods:

  • Collated learnings from existing biofoundry initiatives.
  • Analysis of key operational and strategic factors.
  • Review of community engagement and biosecurity protocols.

Main Results:

  • Identified essential considerations: drivers, institutional/funding models, personnel, hardware/software, data management, interoperability, client engagement, and biosecurity.
  • Highlighted the critical need for long-term business models and financial sustainability.
  • Emphasized the importance of community outreach and engagement with existing facilities.

Conclusions:

  • Successful biofoundry establishment demands strategic planning regarding financial investment and operational complexities.
  • Sustained engagement with the research community is vital for client base growth.
  • Collaboration with existing facilities, like the Global Biofoundries Alliance, is recommended for integrating state-of-the-art technology.