Giant and multiple cardiac papillary fibroelastomas masquerading as acute cerebrovascular events

Area of Science:

• Cardiology
• Oncology
• Pathology

Background:

• Cardiac papillary fibroelastomas (CPF) are uncommon benign neoplasms of the heart.
• These tumors are clinically significant due to their high embolic potential, leading to severe complications.
• While rare, CPF can present with varying sizes and numbers, posing diagnostic and therapeutic challenges.

Purpose of the Study:

• To report two rare cases of cardiac papillary fibroelastomas.
• To emphasize the unusual size and multiplicity of these tumors in the presented cases.
• To discuss the clinical implications and management of such rare presentations.

Main Methods:

• Case report presentation.
• Review of clinical data and imaging findings.
• Pathological examination of resected tumors (if applicable).

Main Results:

• Two patients presented with cardiac papillary fibroelastomas.
• The tumors were notably large and multiple, which is an infrequent occurrence.
• Embolic events or risk thereof were a primary clinical concern.

Conclusions:

• Cardiac papillary fibroelastomas, despite being benign, require careful management due to embolic risks.
• Unusually large or multiple CPF represent a rare but significant clinical scenario.
• Early diagnosis and appropriate intervention are crucial for preventing embolic complications.