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Related Concept Videos

Ultrasonography01:17

Ultrasonography

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Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called...
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Related Experiment Video

Updated: Nov 10, 2025

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
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Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

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Extra-Thyroid Extension Prediction by Ultrasound Quantitative Method Based on Thyroid Capsule Response Evaluation.

Minghang Lin1,2, Yiming Su3, Weili Wei2

  • 1Department of Ultrasound, Fuqing City Hospital Affiliated with Fujian Medical University, Fuzhou, Fujian, China (mainland).

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
|April 5, 2021
PubMed
Summary
This summary is machine-generated.

The L/V ratio, a novel ultrasound measurement, accurately predicts extra-capsular invasion in thyroid nodules. This quantitative method surpasses subjective visual assessment for determining thyroid cancer spread.

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Area of Science:

  • Radiology
  • Oncology
  • Medical Imaging

Background:

  • Thyroid nodules require accurate assessment for malignancy and local invasion.
  • Determining extra-capsular invasion (ETE) is crucial for surgical planning and prognosis.
  • Current methods for assessing ETE can be subjective.

Purpose of the Study:

  • To evaluate the efficacy of ultrasound quantification, specifically the L/V ratio, in predicting extra-capsular invasion of thyroid nodules.
  • To compare the predictive power of the L/V ratio against the aspect ratio (AR) and manual judgment.

Main Methods:

  • Ultrasound examination of 145 patients with preoperatively diagnosed malignant thyroid nodules.
  • Calculation of the L/V ratio (ledge length/vertical diameter) and aspect ratio (AR).
  • Comparison of L/V ratio, AR, and subjective visual assessment in predicting extra-thyroid extension (ETE).

Main Results:

  • Extra-capsular invasion was significantly associated with the L/V ratio.
  • The L/V ratio demonstrated superior predictive ability for ETE compared to AR and manual judgment.
  • A L/V ratio threshold of 0.2325 with a Youden index of 0.593 was identified.

Conclusions:

  • The L/V ratio is a precise ultrasound-based quantitative tool for predicting ETE in thyroid malignancies.
  • This method offers an objective alternative to subjective visual assessment for evaluating thyroid capsule interaction.
  • Further validation across a broader range of cases is recommended.