Related Experiment Video
Updated: Nov 10, 2025

Author Spotlight: Comparing Alveolar and Long Bone Remodeling to Explore OTM Model Potential
Published on: July 21, 2023
Numerical simulations on periprosthetic bone remodeling: a systematic review
Agostino Igor Mirulla1, Salvatore Pinelli2, Stefano Zaffagnini3
1Department of Engineering, University of Palermo, Viale delle Scienze Ed.8, 90128 Palermo, Italy; Department of Biomedical and Neurmotor Sciences, University of Bologna, Via G. Pupilli 1, 40136 Bologna, Italy.
This review highlights the growing use of finite element (FE) simulation for analyzing periprosthetic bone remodeling. Researchers are exploring various methods, but a balance between accuracy and computational cost is crucial for effective simulation.
Area of Science:
- Biomechanical Engineering
- Computational Mechanics
- Orthopedic Research
Background:
- Periprosthetic bone remodeling is a critical factor in implant longevity.
- Finite element (FE) simulation offers a powerful tool for analyzing bone response around implants.
Purpose of the Study:
- To systematically review the literature on finite element (FE) simulation of periprosthetic bone remodeling.
- To identify trends and common methodologies in FE analysis of bone remodeling around prostheses.
Main Methods:
- A systematic literature review was performed across 9 databases from 2009 to 2020.
- Inclusion criteria focused on English full-text articles with relevant keywords in title and abstract.
- Articles were classified by simulation dimensionality, interface modeling, output parameters, prosthesis type, and bone remodeling algorithms.
Main Results:
- Sixty-seven studies met the inclusion criteria.
- Femur and tooth were the most analyzed bone segments.
- Three-dimensional simulations and bone density variation were common analysis methods, with bonded interfaces frequently employed.
Conclusions:
- There is a rising interest in FE analysis for bone remodeling across various bone segments.
- Current approaches are heterogeneous, necessitating a balance between computational efficiency and simulation accuracy.
Related Concept Videos
Bone Remodeling
Osteoclasts in Bone Remodeling

