Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ethanol-induced urticaria: a case report.

S Ting1, D O Rauls, P Ashbaugh

  • 1Department of Medicine, Allergy and Immunology Service, William Beaumont Army Medical Center, El Paso, Texas.

Annals of Allergy
|June 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Managing women with cervical cancer symptoms: Cervical One-Stop Assessment Clinic.

Irish medical journal·2026
Same author

Definition of parameters and thresholds to detect MYCN amplification in retinoblastomas.

Virchows Archiv : an international journal of pathology·2025
Same author

Impact of encorafenib on survival of patients with BRAF<sup>V600E</sup>-mutant metastatic colorectal cancer in a real-world setting.

Journal of cancer research and clinical oncology·2023
Same author

Smaller panel, similar results: genomic profiling and molecularly informed therapy in pancreatic cancer.

ESMO open·2023
Same author

A prognostic systemic inflammation score (SIS) in patients with advanced intrahepatic cholangiocarcinoma.

Journal of cancer research and clinical oncology·2022
Same author

Utilization of the Youth Quitline as an opportunity for an undergraduate nursing students to deliver smoking cessation counseling as their clinical placement: An implementation of a service-learning model.

Nurse education today·2022
Same journal

Hay fever; a review of the literature for 1945.

Annals of allergy·2010
Same journal

Nasal and sputum smears.

Annals of allergy·2010
Same journal

Determination of penicillin-susceptible strains of bacteria.

Annals of allergy·2010
Same journal

Fleabite reactions; clinical and experimental observations and effect of histamine-azoprotein therapy.

Annals of allergy·2010
Same journal

D.H.E. 45 (dihydroergotamine) in the treatment of allergic megraine.

Annals of allergy·2010
Same journal

Antigenicity of proteins in relation to allergy.

Annals of allergy·2010
See all related articles

Ethanol ingestion can trigger rare cases of urticaria (hives). This study found that ethanol directly causes mast cell degranulation and histamine release, leading to hives in a specific patient.

Area of Science:

  • Immunology
  • Dermatology
  • Toxicology

Background:

  • Urticaria, commonly known as hives, is a rare condition triggered by ethanol consumption.
  • The case study focuses on a 36-year-old Caucasian male experiencing generalized pruritic urticarial lesions after consuming alcoholic beverages.

Observation:

  • The patient developed urticarial lesions within 5 to 15 minutes of drinking any type of alcohol.
  • A blinded challenge confirmed that pure ethanol, but not grape juice, induced urticaria and elevated plasma histamine levels.

Findings:

  • Skin prick tests for common allergens including ethanol, acetaldehyde, and acetic acid were negative.
  • Biopsy revealed mast cell degranulation in urticarial lesions, indicating direct mediator release.
  • Ethanol ingestion led to a significant elevation in plasma histamine.

Related Experiment Videos

Implications:

  • Ethanol appears to directly trigger mast cell degranulation and histamine release via non-immunoglobulin E (non-IgE) mediated mechanisms.
  • Antihistamine treatment, specifically Hydroxyzine, effectively inhibited the ethanol-induced skin response and histamine release.
  • This case highlights a rare hypersensitivity to ethanol, emphasizing the need for thorough allergen investigation in unexplained urticaria.