Related Experiment Video
Updated: Nov 10, 2025

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology
Published on: December 1, 2023
Modeling partial lockdowns in multiplex networks using partition strategies
Adrià Plazas1,2, Irene Malvestio1,2, Michele Starnini3
1Departament de Física de la Matèria Condensada, Universitat de Barcelona, 08028 Barcelona, Catalonia Spain.
Abstract:
National stay-at-home orders, or lockdowns, were imposed in several countries to drastically reduce the social interactions mainly responsible for the transmission of the SARS-CoV-2 virus. Despite being essential to slow down the COVID-19 pandemic, these containment measures are associated with an economic burden. In this work, we propose a network approach to model the implementation of a partial lockdown, breaking the society into disconnected components, or partitions. Our model is composed by two main ingredients: a multiplex network representing human contacts within different contexts, formed by a Household layer, a Work layer, and a Social layer including generic social interactions, and a Susceptible-Infected-Recovered process that mimics the epidemic spreading. We compare different partition strategies, with a twofold aim: reducing the epidemic outbreak and minimizing the economic cost associated to the partial lockdown. We also show that the inclusion of unconstrained social interactions dramatically increases the epidemic spreading, while different kinds of restrictions on social interactions help in keeping the benefices of the network partition.
Supplementary Information:
The online version contains supplementary material available at 10.1007/s41109-021-00366-7.
Related Concept Videos
Multimachine Stability
In analyzing the system, the nodal equations represent the relationship between bus voltages, machine voltages, and machine currents. The nodal equation is given by:
Masking and Demasking Agents
There are many masking agents, such as cyanide, fluoride, triethanolamine, thiourea, and 2,3-bis(sulfanyl)propan-1-ol (formerly 2,3-dimercapto-1-propanol), with the masking agent chosen based on...
Zones of Protection
Protective zones are defined by closed dashed lines, containing one or more components. A key characteristic of these zones is the strategic placement of...
Multicompartment Models: Overview
These models offer a more comprehensive representation of drug behavior in the body than one-compartment models. They accommodate the complexity of drug distribution,...
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
Block Diagram Reduction
The first step in this process is the identification and relocation of a branch point. A branch point, where a...

