Management of osteoporosis in older men

Jean-Marc Kaufman1

  • 1Department of Endocrinology, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Gent, Belgium. jean.kaufman@ugent.be.

Insights

Osteoporosis affects one in three men, leading to worse outcomes for fractures. Early diagnosis and treatment are crucial but underutilized in older men.

Area of Science:

  • Gerontology
  • Orthopedics
  • Endocrinology

Background:

  • Osteoporosis and fragility fractures pose significant health risks for older men, with poorer outcomes compared to women.
  • Despite available diagnostic tools and treatments, a small percentage of high-risk older men receive osteoporosis therapy.
  • The societal and individual burden of osteoporosis in men necessitates improved management strategies.

Purpose of the Study:

  • To review the current evidence on osteoporosis and fragility fractures in older men.
  • To highlight the burden, pathophysiology, diagnosis, and management of osteoporosis in this demographic.
  • To inform clinical practice and research regarding male osteoporosis.

Main Methods:

  • This narrative review synthesizes existing literature on osteoporosis in older men.
  • It covers epidemiology, pathophysiology, clinical presentation, risk assessment, and treatment options.
  • Evidence from clinical trials and observational studies is summarized.

Main Results:

  • Fragility fractures are common in older men, with hip fractures having worse outcomes than in women.
  • Underdiagnosis and undertreatment of osteoporosis are prevalent in high-risk older men.
  • Effective diagnostic tools and therapeutic agents are available but underutilized.

Conclusions:

  • Osteoporosis in older men is a significant, under-addressed health issue.
  • Improved awareness, risk assessment, and timely treatment are essential for better patient outcomes.
  • Further research is needed to strengthen the evidence base for managing male osteoporosis.

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