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Related Concept Videos

Sutures of the Skull01:22

Sutures of the Skull

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The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
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Related Experiment Video

Updated: Nov 10, 2025

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

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[Interdisciplinary surgery to the central skull base-current status].

J Schipper1, A Albrecht2, T Klenzner2

  • 1Universitätsklinik für Hals‑, Nasen- und Ohrenheilkunde und Poliklinik, Heinrich-Heine-Universität Düsseldorf, Moorenstraße 5, 40255, Düsseldorf, Deutschland. joerg.schipper@med.uni-duesseldorf.de.

HNO
|April 6, 2021
PubMed
Summary
This summary is machine-generated.

This study systematizes surgical access routes for complex central skull base pathologies. Optimal surgical corridors depend on pathology type, location, and functional preservation goals.

Keywords:
Microsurgical visualization proceduresMinimally invasive surgeryMultiport access routesPathologies of the central skull basePowered instruments

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Area of Science:

  • Neurosurgery
  • Otorhinolaryngology
  • Head and Neck Surgery

Background:

  • The skull base presents surgical complexity, often requiring combined access routes.
  • Advancements in microsurgical techniques and multiport accesses create less invasive surgical corridors.
  • Effective treatment necessitates close interdisciplinary collaboration between ENT and neurosurgeons.

Purpose of the Study:

  • To systematize established surgical access routes to the central skull base.
  • To discuss these routes in relation to specific pathologies and current research.
  • To provide a framework based on clinical experience for complex skull base surgeries.

Main Methods:

  • Retrospective, qualitative, and descriptive evaluation of surgical reports.
  • Analysis of patient data jointly treated by neurosurgery and ENT/head and neck surgery from 2006 to 2019.
  • Categorization of surgical access routes based on clinical experience.

Main Results:

  • Surgical access routes include transnasal-transsphenoidal, subfrontal, subtemporal, transzygomatic, transpterygonal, transpetrous, translabyrinthine, and suboccipital.
  • Access route selection was determined by pathology location, type (inflammatory, benign/malignant tumor), and functional preservation goals.
  • Multiport access routes, sometimes in combination, were utilized.

Conclusions:

  • Central skull base surgery is challenging due to complex structures and diverse pathologies.
  • Specialized expertise from multiple medical disciplines is crucial for successful outcomes.
  • Surgery should be centralized at certified competence centers, adhering to German Society of Skull Base Surgery criteria.