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Atherosclerotic Cardiovascular Disease in Individuals with Hepatitis C Viral Infection

Alison L Bailey1, Saif Al-Adwan2, Eliea Sneij3

  • 1Centennial Heart at Parkridge, HCA Healthcare, 2205 McCallie Avenue, Chattanooga, TN, 37404, USA. dr.alison.bailey@icloud.com.

Current Cardiology Reports
|April 6, 2021
PubMed

Insights

Hepatitis C virus (HCV) infection is linked to a higher risk of atherosclerotic cardiovascular disease (ASCVD). Increased awareness and risk-lowering strategies are crucial for managing this growing patient population.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • Hepatitis C virus (HCV) affects over 70 million people globally.
  • Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of mortality worldwide.
  • A significant association between HCV infection and atherosclerosis has been established.

Purpose of the Study:

  • To review recent studies on the association between HCV infection and ASCVD risk.
  • To highlight the increased burden of atherosclerosis in HCV-infected individuals.
  • To discuss the implications of expanded HCV screening on cardiovascular risk management.

Main Methods:

  • Review of current scientific literature and epidemiological studies.
  • Analysis of data linking HCV infection to subclinical ASCVD and cardiovascular events.
  • Synthesis of findings regarding the prevalence and impact of atherosclerosis in HCV patients.

Main Results:

  • HCV infection is associated with an increased risk of subclinical ASCVD.
  • Individuals with HCV experience a higher incidence of cardiovascular events.
  • The burden of atherosclerosis is notably higher in the HCV-infected population.

Conclusions:

  • HCV infection poses a significant cardiovascular risk, necessitating proactive management.
  • Expanded HCV screening will likely increase the number of individuals at risk.
  • Healthcare professionals require education on managing CV risk in HCV patients.
Abstract

Keywords:
Atherosclerosis, inflammation, Direct-acting antiviralCardiovascular diseaseHepatitis C virus

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