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Updated: Nov 10, 2025

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Published on: April 7, 2023
The antimicrobial effect behind Cannabis sativa.
Laureano Schofs1,2, Mónica D Sparo2,3, Sergio F Sánchez Bruni1,2
1Laboratory of Pharmacology, Faculty of Veterinary Medicine, Universidad Nacional del Centro de la Provincia de Buenos Aires, Tandil, Argentina.
Cannabis sativa extracts show antimicrobial potential against drug-resistant bacteria and fungi. Further research into its cannabinoids and terpenes could yield novel antimicrobial agents.
Area of Science:
- Pharmacology
- Microbiology
- Ethnobotany
Background:
- Multidrug-resistant bacteria pose a significant global health threat, necessitating novel antimicrobial strategies.
- Cannabis sativa has historical medicinal uses, including for infections, suggesting potential antimicrobial properties.
Purpose of the Study:
- To review the antimicrobial activity of Cannabis sativa extracts.
- To evaluate the efficacy of its main components, cannabinoids and terpenes, against pathogenic bacteria and fungi.
Main Methods:
- Literature review of studies investigating Cannabis sativa extracts.
- Analysis of research on the antimicrobial effects of cannabinoids and terpenes.
- Assessment of activity against various bacterial and fungal pathogens.
Main Results:
- Cannabis sativa extracts demonstrate broad-spectrum activity against numerous bacterial and fungal strains.
- Specific cannabinoids and terpenes exhibit potent antimicrobial effects.
- The plant's components show promise in combating multidrug-resistant microorganisms.
Conclusions:
- Cannabis sativa represents a potential source for new antimicrobial agents.
- Further investigation into cannabinoids and terpenes could lead to the development of novel therapeutics.
- This review highlights the need for continued research into phytomedicines for infectious diseases.
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