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Updated: Nov 10, 2025

Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice
Published on: July 5, 2021
[Sinus node dysfunction associated with cardiac sarcoidosis: A case report]
L-D Azoulay1, D Perrot1, A Sharifzadehgan1
1Service de cardiologie, unité de rythmologie, hôpital européen Georges-Pompidou, Université de Paris, Assistance publique-Hôpitaux de Paris, 75015 Paris, France.
Introduction:
Sarcoidosis is a multisystemic granulomatous disease of unknown cause occurring in young adults. Cardiac sarcoidosis patients are at increased risk for atrioventricular blocks and ventricular arrhythmias. Sinus node dysfunction is scarcely reported.
Observation:
We report a case of cardiac sarcoidosis revealed by a sinus node dysfunction and focus on cardiac and thoracic imaging to guide diagnosis.
Conclusion:
Sinus node dysfunction may be the first manifestation of cardiac sarcoidosis. In unexplained sinus node dysfunction in young patients, advanced cardiac imaging is a key to cardiac sarcoidosis diagnostic. Early recognition of cardiac sarcoidosis enables to start immunosuppressive treatment and discuss implantable cardioverter defibrillator implantation.
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