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Related Concept Videos

ECG Interpretation of Arrhythmias I: Sinus Arrhythmias01:16

ECG Interpretation of Arrhythmias I: Sinus Arrhythmias

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Arrhythmias are disturbances in the heart's rhythm that lead to abnormal heartbeats. These irregularities can originate from different parts of the heart and are classified based on their origin and nature.
Types of Arrhythmias
Sinus Node Arrhythmias
Sinus Bradycardia: Originating from the sinoatrial (SA) node, sinus bradycardia involves slower impulses, resulting in a heart rate of less than 60 beats per minute (bpm). Causes include sleep, vagal stimulation, beta-blockers, hypothyroidism,...
534
Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

Dysrhythmias IV: Characteristics of Bradyarrhythmias

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Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
277
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

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Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
125
Mechanism of Cardiac Arrhythmias01:28

Mechanism of Cardiac Arrhythmias

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Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
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Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

166
Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
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Updated: Nov 10, 2025

Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice
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[Sinus node dysfunction associated with cardiac sarcoidosis: A case report].

L-D Azoulay1, D Perrot1, A Sharifzadehgan1

  • 1Service de cardiologie, unité de rythmologie, hôpital européen Georges-Pompidou, Université de Paris, Assistance publique-Hôpitaux de Paris, 75015 Paris, France.

La Revue De Medecine Interne
|April 7, 2021
PubMed
Summary
This summary is machine-generated.

Sinus node dysfunction can be an early sign of cardiac sarcoidosis in young adults. Advanced cardiac imaging is crucial for diagnosing this condition and initiating timely treatment.

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Area of Science:

  • Cardiology
  • Immunology
  • Radiology

Background:

  • Sarcoidosis is a multisystemic granulomatous disease affecting young adults.
  • Cardiac sarcoidosis increases risks for atrioventricular blocks and ventricular arrhythmias.
  • Sinus node dysfunction is an uncommon presentation of cardiac sarcoidosis.

Observation:

  • Presents a case of cardiac sarcoidosis initially manifesting as sinus node dysfunction.
  • Highlights the role of cardiac and thoracic imaging in diagnosis.

Findings:

  • Sinus node dysfunction can be the primary presenting symptom of cardiac sarcoidosis.
  • Advanced cardiac imaging aids in diagnosing cardiac sarcoidosis in unexplained cases.

Implications:

  • Early diagnosis of cardiac sarcoidosis allows for prompt immunosuppressive therapy.
  • Facilitates discussion regarding implantable cardioverter-defibrillator (ICD) implantation.
  • Emphasizes the importance of considering cardiac sarcoidosis in young patients with unexplained sinus node dysfunction.