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[Comparison of conformation characteristics of bradykinin and igercin molecules]
Bioorganicheskaia Khimiia
|March 1, 1988
Abstract:
A certain resemblance of three-dimensional molecular organizations of the known peptide bioregulator bradykinin (Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg) and the tentative cytophilic centre of the human IgE igercin (Arg-Ala-Val-Ser-Val-Asn-Pro-Gly-Lys) existing along with their pronounced structural similarity was shown by means of energy calculations. This is, however, not the case with the "biologically active" bradykinin conformations suggested earlier.