Determining the relation between total knee arthroplasty surgery site drainage in two weeks after surgery with

Mehdi Motififard1, Khalilolah Nazem1, Mehdi Meshkati2

  • 1Department of Orthopedic and Trauma, Isfahan University of Medical Science Isfahan, Iran.

Insights

Bloody purulent discharge lasting over seven days after total knee arthroplasty (TKA) may indicate infection. Longer discharge duration and specific discharge types are linked to prosthetic joint infection (PJI) and superficial infections.

Area of Science:

  • Orthopedic Surgery
  • Infectious Disease
  • Arthroplasty Research

Background:

  • Prosthetic joint infection (PJI) is a severe complication following total knee arthroplasty (TKA).
  • Early diagnosis and treatment of PJI are crucial for patient outcomes.
  • The relationship between surgical site discharge characteristics and PJI has not been previously studied.

Purpose of the Study:

  • To investigate the association between surgical site discharge characteristics (type and duration) and the incidence of PJI after TKA.
  • To identify potential risk factors for PJI and superficial infections in TKA patients.

Main Methods:

  • A longitudinal observational study involving 961 elective TKAs performed on 850 patients between 2017 and 2019.
  • Patients were followed for two years post-surgery to collect data on discharge occurrence, type, duration, and infection rates.
  • Data analysis focused on correlating discharge characteristics with the incidence of PJI and superficial infections.

Main Results:

  • The incidence rates for superficial infections and PJI were both 0.3%.
  • Patients with infections (PJI or superficial) exhibited significantly longer discharge durations (14.6 days for PJI, 13.3 days for superficial infections) compared to the overall study population (7.7 days).
  • Bloody-purulent discharge was identified as a significant indicator associated with the development of both PJI and superficial infections.

Conclusions:

  • Bloody purulent discharge persisting for seven days or more post-TKA is a strong indicator of potential PJI or superficial infection.
  • While discharge characteristics suggest infection, they cannot reliably differentiate between PJI and superficial types.
  • Additional risk factors for infection include female gender, longer surgical times, extended hospitalization, and prolonged discharge duration.
Abstract

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