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Updated: Nov 9, 2025
The Use of Reverse Phase Protein Arrays RPPA to Explore Protein Expression Variation within Individual Renal Cell Cancers
Published on: January 22, 2013
[Histological subtypes of renal cell carcinoma : Overview and new developments]
I Polifka1, A Agaimy1, H Moch2
1Pathologisches Institut, Universitätsklinikum Erlangen, Krankenhausstr. 8-10, 91054, Erlangen, Deutschland.
Background:
The classification of renal cell carcinoma (RCC) has changed remarkably in recent years.
Objectives:
This is a short overview of the classification of RCC, focusing on new developments.
Materials And Methods:
A literature search was performed resulting in an overview of the classification of RCC. Emerging entities were discussed in detail.
Results:
Apart from the RCC subtypes in the WHO classification of 2016, several emerging entities came up over the last few years that are characterized by typical morphology, immunophenotype, and especially specific genetic alterations.
Conclusion:
Precise classification of RCC is the key to better prognostic assessment with potential tumor-specific therapy and plays an important role in the recognition of possible association with hereditary tumor syndromes.
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