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Updated: Nov 9, 2025
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[Study on Proficiency Testing of Determination Potassium in Serum]
Ting Yu1, Liying Ma1, Juanli Zhang2
1National Institutes for Food and Drug Control, Beijing, 100050.
Summary
This study assessed laboratory performance in serum potassium testing through proficiency testing (PT). Most laboratories demonstrated accurate and reliable results, indicating good overall testing quality.
Area of Science:
- Clinical Chemistry
- Laboratory Medicine
- Analytical Chemistry
Background:
- Proficiency testing (PT) is crucial for assessing and improving laboratory performance.
- Accurate determination of serum potassium is vital for patient diagnosis and management.
- Standardized evaluation methods ensure the reliability of laboratory testing.
Purpose of the Study:
- To evaluate the analytical capacity of laboratories performing serum potassium determination via PT.
- To enhance the overall quality of potassium testing in participating laboratories.
- To provide targeted technical recommendations for laboratories with unsatisfactory performance.
Main Methods:
- Homogeneity and stability of PT samples were assessed using ANOVA and t-tests.
- Assigned values for PT samples were determined by a reference method.
- Acceptable performance criteria included a deviation within ±15.0% and precision < 3.0%.
Main Results:
- All laboratories submitted valid data for the serum potassium proficiency testing.
- One laboratory did not meet the performance criteria, resulting in a 90.9% satisfaction rate.
- The majority of laboratories demonstrated accurate and reliable potassium measurements.
Conclusions:
- Most laboratories possess accurate and reliable capabilities for serum potassium determination.
- The PT program effectively identified areas for quality improvement.
- Continued monitoring and support are recommended for laboratories needing enhancement.
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