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Related Experiment Video

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The Precentral Insular Cortical Network for Speech Articulation.

Francesco Tomaiuolo1, Serena Campana2, Loredana Voci2

  • 1Department of Clinical and Experimental Medicine, Messina University, Piazza Pugliatti, 1 Messina, Italy 98122.

Cerebral Cortex (New York, N.Y. : 1991)
|April 7, 2021
PubMed
Summary
This summary is machine-generated.

Speech apraxia, a motor speech disorder, is linked to specific left hemisphere brain regions. Lesions in the insula and surrounding areas, not Broca's area, are critical for speech motor control.

Keywords:
circuit for speech praxislanguage productionphonic articulationspeech apraxia

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Area of Science:

  • Neuroscience
  • Speech-Language Pathology

Background:

  • Apraxia of speech is a motor disorder affecting speech articulation.
  • Previous studies struggled to pinpoint critical brain areas due to co-occurring aphasia.

Purpose of the Study:

  • To identify the specific cortical areas responsible for pure speech apraxia.
  • To differentiate the neural basis of speech motor execution from language processing.

Main Methods:

  • Case study of four patients with pure speech apraxia.
  • Detailed lesion analysis in the left hemisphere.

Main Results:

  • All patients had critical lesions in the left precentral gyrus of the insula (gyrus brevis III).
  • Associated damage included the subcentral opercular cortex and inferior central sulcus (orofacial representation).
  • No damage was observed in Broca's area.

Conclusions:

  • The insula and connected regions form a critical circuit for speech motor coordination.
  • This circuit is distinct from the neural networks involved in language cognition, such as Broca's area.