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Updated: Nov 9, 2025
A Murine Tail Lymphedema Model
Published on: February 10, 2021
Vascularized omental lymphatic transplant for upper extremity lymphedema: A systematic review
Nicholas R Jarvis1, Ricardo A Torres2, Francisco R Avila2
1Mayo Clinic Alix School of Medicine, Mayo Clinic, Scottsdale, Arizona, USA.
Background:
Vascularized omental lymphatic transplant (VOLT) is an increasingly popular treatment of extremity lymphedema given its promising donor site. While the success of VOLT in the treatment of lymphedema has been reported previously, several questions remain.
Aim:
To further elucidate appropriate use of VOLT in the treatment of lymphedema, specifically addressing patient selection, harvest technique, and operative methods.
Methods And Results:
A systematic review of VOLT for upper extremity lymphedema was performed. Of 115 yield studies, seven were included for analysis based on inclusion and exclusion criteria. Included studies demonstrated significant reductions in extremity circumference/volume (average volume reduction, 22.7%-39.5%) as well as subjective improvements using patient-reported outcomes. Though studies are heterogenous and limited, when analyzed in aggregate, suggest the efficacy of VOLT in lymphedema treatment.
Conclusion:
This is the largest systematic review of VOLT to date. VOLT continues to show promise as a safe and efficacious surgical intervention for lymphedema in the upper extremity. Further studies are warranted to more definitively identify patients for whom this technique is appropriate as well as ideal harvest and inset technique.
