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SARS-CoV-2 Not Detectable in Ocular Specimens of a Patient with a Past Infection
Tina Felfeli1,2, Tony Mazzulli3,4, Shawn T Clark3
1Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada.
Abstract:
Purpose: To present a a case study that aims to investigate the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the ocular tissue samples of a patient previously infected with COVID-19 and determine its transmissibility.Study Design: Case ReportResults: In this case study, SARS-CoV-2 was not detected in the vitreous and uveal tissue samples by RT-PCR for detection of three gene targets in a patient with a past COVID-19 infection 15 days prior to presention with a globe rupture.Conclusions: Our findings suggest that patients with long-term existence of SARS-CoV-2 at low detectable levels may not have active intraocular viral shedding. This is of particular importance as ophthalmic surgical procedures may potentiate virus spread from patients infected with SARS-CoV-2.
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