Related Experiment Video
Updated: Nov 9, 2025
Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts
Published on: March 26, 2015
Histologic Evaluation of Tibial Attachment in 11-Year Double-Bundle ACL Reconstruction with Hamstring Tendons: A Case
Yuki Okazaki1,2, Nobuhiro Abe1, Kimihiko Makiyama1
1Department of Orthopaedic Surgery and Sport Medicine, Kawasaki Medical School General Medical Center, Okayama, Japan.
Case:
A 49-year-old woman injured her anterior cruciate ligament (ACL) as a high-school student. Double-bundle ACL reconstruction (DBACLR) using hamstring tendon grafts was performed because of recurrent instability. Eleven years after DBACLR, total knee arthroplasty was performed because of osteoarthritis progression. Histologic analysis was completed to observe the osteointegration of the tendon in the obtained proximal tibia. The tibial tunnel showed Sharpey-like fibers anteriorly, connecting the tendon graft and lamellar bone, whereas the intraarticular exit revealed well-aligned chondrocytes posteriorly, indicating chondral metaplasia of the tendon graft.
Conclusion:
Tendon-bone healing can regenerate both fibrous insertion and chondral metaplasia in DBACLR.
