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Updated: Aug 9, 2026

The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo
Published on: August 2, 2017
[Structural basis of compensatory-adaptive reactions of the human placenta]
25 placentas from pregnant women with preeclampsia and 18 women with uncomplicated pregnancy (control) were studied morphologically, using stereohistometric method. It was determined that placenta is a polyfunctional organ which is organized in such a way that the same morphological structures (chorionic epithelium, interstitium, capillaries) can perform different functions--transport, barrier, hormone. With the development of compensatory-adaptation reactions, structural placenta features determine the possibility to decrease the efficiency of some functions and increase the efficiency of others. These facts should be taken into consideration during the analysis of morphological placenta changes caused by the diseases of the mother and fetus.
25 placentas from pregnant women with preeclampsia and 18 women with uncomplicated pregnancy (control) were studied morphologically, using stereohistometric method. It was determined that placenta is a polyfunctional organ which is organized in such a way that the same morphological structures (chorionic epithelium, interstitium, capillaries) can perform different functions--transport, barrier, hormone. With the development of compensatory-adaptation reactions, structural placenta features determine the possibility to decrease the efficiency of some functions and increase the efficiency of others. These facts should be taken into consideration during the analysis of morphological placenta changes caused by the diseases of the mother and fetus.
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