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Updated: Nov 9, 2025

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Published on: June 8, 2017
Investigation of the effectiveness of a new portable 'cryopen' probe for cryotherapy (CryoTreq®)
Peter Stalmans1, Joris Vander Mijnsbrugge2,3, Filip D'Hollander3
1Dept. Ophthalmology UZ Leuven, Herestraat 49, 3000, Leuven, Belgium. peter.stalmans@uzleuven.be.
Background:
To test the effectiveness of a new, innovative, single-use handheld 'cryopen' (CryoTreq®), which has been developed and marketed by Vitreq.
Methods:
Animal testing of cryopexy using the Cryotreq ® in two pig eyes was performed.
Results:
The biological effects of cryopexy were observed.
Conclusions:
During the surgery, the handheld device was comfortable to use and offers the surgeon more freedom to move. The cryotherapy caused severe atrophy and thinning of retinal layers, pigment epithelium and choroidea in a relatively uniform thickness. The cryopen is effective and offers advantages over non-handheld cryotherapy devices.

