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Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals
Published on: September 20, 2021
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Herpes simplex virus esophagitis-clinical challenges in the elderly
Sara Fernandes Custódio1, Catarina Félix2, Fátima Cruz3
1Department of Otorhinolaryngology, Centro Hospitalar de Lisboa Ocidental EPE Hospital de Egas Moniz, Lisboa, Portugal saracustodio1@gmail.com.
BMJ Case Reports
|April 8, 2021
Summary
Herpetic esophagitis, caused by herpes simplex virus, can present with vague symptoms like anorexia in elderly patients. Early diagnosis and treatment with acyclovir are crucial for managing this condition.
Area of Science:
- Gastroenterology
- Virology
- Geriatrics
Background:
- Elderly patients on systemic corticosteroids are susceptible to opportunistic infections.
- Herpes simplex virus (HSV) esophagitis is a potential complication, often presenting atypically in older adults.
Observation:
- A 77-year-old woman on corticosteroids presented with non-specific symptoms including malaise, anorexia, and gastrointestinal distress.
- She later developed severe dysphagia, prompting an upper gastrointestinal endoscopy (UGE).
Findings:
- UGE revealed shallow ulcers in the esophagus, with histological examination confirming herpes simplex virus esophagitis.
- The patient's initial symptoms were non-specific, with dysphagia appearing as a late manifestation.
Implications:
- This case highlights the importance of considering HSV esophagitis in elderly patients with atypical presentations.
- Prompt diagnosis and treatment with antiviral therapy, such as intravenous acyclovir, are essential for favorable outcomes.
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