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Serrating through vascular access catheters: a great masquerader with severe systemic manifestations

Smit Sunil Deliwala1, Murtaza Hussain1, Anoosha Ponnapalli1

  • 1Internal Medicine, Hurley Medical Center, Flint, Michigan, USA.

BMJ Case Reports
|April 8, 2021
PubMed

Insights

Serratia marcescens frequently infects catheters, causing severe recurrent bloodstream infections and abscesses. Eradicating these challenging Serratia infections requires a comprehensive strategy for identification, treatment, and surveillance.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Clinical Medicine

Background:

  • Serratia marcescens is a common cause of hospital-acquired infections, particularly associated with vascular access catheters.
  • Catheter-associated infections by Serratia marcescens can lead to severe patient outcomes and outbreaks.

Observation:

  • Presents a unique and severe case of recurrent Serratia marcescens infection.
  • Characterized by persistent bacteremia, hematogenous dissemination, and extensive abscess formation.
  • Highlights the microorganism's virulence and deep-seeding capabilities, leading to challenging eradication.

Findings:

  • Demonstrates the significant difficulty in eradicating Serratia marcescens infections due to multiple virulence factors.
  • Reports a degree of infection severity and dissemination not previously documented in the literature.
  • Emphasizes the need for a multifaceted approach to manage these infections.

Implications:

  • Stresses the importance of intricate identification, therapeutic strategies, and surveillance for Serratia infections.
  • Suggests a gap in current literature regarding comprehensive management protocols for severe Serratia cases.
  • Underscores the need for further research and reporting on effective interventions against this resilient pathogen.
Keywords:
general practice / family medicineinfection (gastroenterology)infection control in hospitalnosocomial infectionsvalvar diseases

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