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A Protocol to Acquire the Degenerative Tenocyte from Humans
Published on: June 9, 2018
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Recurrent Nontuberculous Mycobacterial Tenosynovitis.
Melissa Kwan1, Richard Tupler1
1Department of Radiology, Ochsner Clinic Foundation, New Orleans, LA.
Ochsner Journal
|April 8, 2021
Summary
Nontuberculous mycobacterial musculoskeletal infections, like Mycobacterium avium complex tenosynovitis, are challenging to treat. Recurrent infections highlight the need for improved diagnostic and therapeutic strategies.
Area of Science:
- Infectious Diseases
- Orthopedic Surgery
- Microbiology
Background:
- Nontuberculous mycobacteria (NTM) are infrequent causes of musculoskeletal infections.
- Diagnosis is often delayed, and treatment is complicated by drug resistance and the need for combined medical and surgical interventions.
Observation:
- A case of recurrent Mycobacterium avium complex (MAC) tenosynovitis in an 88-year-old male is presented.
- The patient underwent multiple treatment courses including pharmacologic therapy and surgical debridement without complete resolution.
Findings:
- Musculoskeletal infections caused by NTM present significant diagnostic and therapeutic challenges.
- Treatment failure rates remain high, especially for rapidly growing mycobacteria such as MAC.
Implications:
- This case underscores the difficulties in managing NTM musculoskeletal infections.
- Further research into novel therapeutic approaches and diagnostic tools for NTM infections is warranted.
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