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A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma DIPG
Published on: March 7, 2017
About a rare pediatric case of myxoid meningioma
Aziz Bedioui1, Mouna Rkhami2, Nesrine Jemel2
1Neurosurgery Department, Trauma Center, Ben Arous, Tunisia. abedioui@gmail.com.
Abstract:
Intracranial meningiomas are uncommon in the pediatric group. Myxoid meningioma is a subtype of metaplastic meningioma. It is the rarest WHO grade I meningioma. Only one case of pediatric myxoid meningioma was described in the literature. We report the case of 14-year-old boy who presented with a left parietal dura-inserted tumor. Histological and immunological studies concluded to a myxoid meningioma. We reviewed the literature for this rare pathology and draw attention to the necessity of distinguishing it from other mucinous tumors of the central nervous system, especially chordoid meningioma which has poorer prognosis.
Insights
Pediatric myxoid meningioma, a rare WHO grade I tumor, is described in a 14-year-old boy. This case highlights the importance of differentiating it from similar central nervous system tumors.
Area of Science:
- Neuro-oncology
- Pediatric Pathology
- Surgical Neurology
Background:
- Intracranial meningiomas are rare in children.
- Myxoid meningioma is an exceptionally rare subtype of WHO grade I meningioma.
- Previous literature documented only one pediatric case.
Observation:
- A 14-year-old male presented with a left parietal dura-inserted tumor.
- Histological and immunohistochemical analyses confirmed a myxoid meningioma.
- This represents the second reported case of pediatric myxoid meningioma.
Findings:
- The tumor was definitively diagnosed as myxoid meningioma.
- A comprehensive literature review was conducted on this rare entity.
- Key diagnostic criteria were identified to distinguish it from other mucinous CNS tumors.
Implications:
- Accurate diagnosis is crucial for appropriate patient management.
- Distinguishing myxoid meningioma from chordoid meningioma is vital due to prognosis differences.
- This case adds to the limited understanding of pediatric myxoid meningiomas.
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