Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History

COPD: Pathogenesis and Clinical Features

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.

Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Editorial for "Longitudinal 1H and 129Xe Lung MRI in Patients With Post-COVID Residual Lung Abnormalities."

Journal of magnetic resonance imaging : JMRI·2026

Same author

Organized Lung Cancer Screening of Subjects Occupationally Exposed to Lung Carcinogens: The LUng Cancer Screening Occupational exposure Study Entry Findings.

JTO clinical and research reports·2026

Same author

Guidance for chest-CT in children and adults with cystic fibrosis: A European perspective (part 2: special situations/respiratory complications).

Respiratory medicine·2026

Same author

Bronchial dilation versus bronchiectasis-lessons learned from Influenza-associated pulmonary aspergillosis.

American journal of respiratory and critical care medicine·2026

Same author

Serious respiratory distress associated with bosentan administration in chronic thromboembolic pulmonary hypertension: A case report.

Therapie·2026

Same author

Clinical applications of co-registered myocardial T2 mapping and dual bright- and black-blood late gadolinium enhancement magnetic resonance imaging.

European heart journal. Imaging methods and practice·2026

Search research articles

Related Experiment Video

Updated: Nov 9, 2025

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Published on: April 12, 2024

Structural and functional changes in COPD: What we have learned from imaging.

Ilyes Benlala¹, François Laurent¹, Gael Dournes¹

¹Centre de recherche Cardio-Thoracique de Bordeaux, University of Bordeaux, INSERM, Bordeaux, France.

Respirology (Carlton, Vic.)

|April 8, 2021

Summary

Chronic obstructive pulmonary disease (COPD) is a major global health issue. Advanced medical imaging like CT and MRI aids in understanding COPD

Keywords:

COPD CT MRI function lung structure

More Related Videos

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Published on: June 21, 2024

Related Experiment Videos

Last Updated: Nov 9, 2025

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Published on: April 12, 2024

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Published on: June 21, 2024

Area of Science:

Pulmonary Medicine
Radiology
Medical Imaging Analysis

Background:

Chronic obstructive pulmonary disease (COPD) is a leading cause of global mortality.
COPD is a complex lung disease with varied manifestations.
Medical imaging and analysis offer new perspectives on COPD assessment.

Purpose of the Study:

To review leading medical imaging techniques for COPD.
To discuss visual and quantitative analysis methods.
To highlight the role of imaging in COPD phenotyping and prognosis.

Main Methods:

Review of computed tomography (CT) and magnetic resonance imaging (MRI) techniques.
Analysis of both qualitative (visual) and quantitative imaging approaches.
Focus on applications in research and clinical settings.

Main Results:

CT and MRI are crucial for evaluating structural and functional lung changes in COPD.
Quantitative imaging analysis provides objective disease metrics.
Imaging findings correlate with patient subgroups and predict disease outcomes.

Conclusions:

Medical imaging, particularly CT and MRI, is essential for comprehensive COPD assessment.
Imaging-based phenotyping improves understanding and management of COPD heterogeneity.
Advanced imaging techniques enhance patient stratification and outcome prediction in COPD.