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PARA-SITE: a computer algorithm for rapidly analyzing the physical-chemical properties of amino acid sequences at
1Department of Biological Chemistry, Washington University School of Medicine, St Louis, MO 63110.
Computer Applications in the Biosciences : CABIOS
|March 1, 1988
Abstract:
A new algorithm is presented which can be used to examine the physical-chemical properties of amino acids at sites of co- or post-translational processing. This algorithm has been incorporated into a computer program known as PARA-SITE. Thirty different parameters can be studied for amino acids which occupy comparable positions in naturally occurring proteins. PARA-SITE should aid in the design and interpretation of protein engineering experiments which seek to dissect structure/activity relationships.