Factors Affecting Morbidity and Mortality after ERCP for Obstructive Jaundice.

Area of Science:

• Gastroenterology
• Endoscopic Procedures
• Biliary and Pancreatic Diseases

Background:

• Endoscopic Retrograde Cholangio Pancreatography (ERCP) is a vital therapeutic tool for obstructive jaundice.
• ERCP is associated with potential patient and procedural complications.
• Identifying factors influencing ERCP outcomes is crucial for patient safety.

Purpose of the Study:

• To determine the factors affecting morbidity and mortality following ERCP in patients with obstructive jaundice.
• To analyze the incidence and types of post-ERCP complications.
• To identify significant predictors of adverse events.

Main Methods:

• Prospective observational study of 30 patients with obstructive jaundice.
• Data collection included patient history, examinations, and ERCP procedural variables.
• Analysis focused on complications such as bleeding and pancreatitis.

Main Results:

• The most common indication for ERCP was sphincterotomy with stone extraction (66.7%).
• 10% of patients developed post-ERCP complications, primarily intra-procedural bleeding (66.7%) and pancreatitis (33.3%).
• Significant predictors of morbidity included middle age, male gender, precut sphincterotomy, and a history of acute pancreatitis.

Conclusions:

• Middle-aged males, precut sphincterotomy, and prior acute pancreatitis are significant predictors of ERCP-related morbidity.
• These findings can inform risk stratification and procedural planning for ERCP.
• Further research with larger cohorts may refine understanding of ERCP complication predictors.