Related Experiment Video
Updated: Nov 9, 2025
Network Pharmacology Prediction and Metabolomics Validation of the Mechanism of Fructus Phyllanthi against Hyperlipidemia
Published on: April 7, 2023
Dose-dependent Effects of Cacao Polyphenol Intake on Lipid Metabolism in Rats
Yuka Aono1, Takanobu Kaido2, Nagisa Kita2
1Anatomy and Physiology Laboratory, Department of Health and Nutrition, Osaka Shoin Women's University, 4-2-26 Hishiya-Nishi, Higashi-Osaka, 577-8550, Japan. aono.yuka@osaka-shoin.ac.jp.
Abstract:
Cacao polyphenols (CPs) are known to suppress the oxidation of low-density lipoprotein and cholesterol absorption. Herein, we examined the impact of CP on the lipid metabolism in rats fed CP-rich chocolate, by analyzing liver weight and histology, via hematoxylin-eosin staining. The high-CP group had significantly lighter livers than the CP-free group. Histologically, the high-CP group showed significantly lower liver fat accumulation than the CP-free group. These results suggest that CPs prevent liver fat accumulation, being potentially useful against obesity and related diseases.
More Related Videos
13:09Rapid Model to Evaluate the Anti-Obesity Potential of a Combination of Syzygium aromaticum Clove and Cuminun cyminum Cumin on C57BL6/j Mice Fed High-Fat Diet
Published on: July 31, 2021
14:39Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults
Published on: April 22, 2022