Myotonic dystrophy of Steinert: are anxiety and depression necessarily concomitants?

Anxio-depressive symptomatology was not found in a small group of thirteen myotonic dystrophy ("Steinert's disease") patients. This contradicts previously published reports which document a moderately severe affective disorder in this disease as well as showing a beneficial clinical response to "imipramine" and "lithium carbonate". Methodologic and interpretative difference may explain the discordance between the studies.