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Updated: Nov 9, 2025

Comparative Lesions Analysis Through a Targeted Sequencing Approach
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Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

Stefan C Dentro1, Ignaty Leshchiner2, Kerstin Haase3

  • 1Cancer Genomics Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK; Big Data Institute, University of Oxford, Oxford OX3 7LF, UK.

Cell
|April 8, 2021
PubMed
Abstract

Keywords:
branching evolutioncancer driver genescancer evolutionintra-tumor heterogeneitypan-cancer genomicssubclonal reconstructiontumor phylogenywhole-genome sequencing

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