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Published on: January 6, 2011
Contribution of mechanical and electrical cardiovascular factors in patients with ischemic stroke
Lavinia Duica1, Elisabeta Antonescu2, Maria Totan3
1Lucian Blaga University of Sibiu, Faculty of Medicine, Sibiu, Romania/ Hospital of Psychiatry, Doctor Gheorghe Preda, Sibiu, Romania.
Insights
Left ventricular hypertrophy (LVH) significantly increases stroke risk, especially when combined with carotid stenosis over 50%. This finding highlights key factors contributing to ischemic stroke.
Area of Science:
- Cardiology
- Neurology
- Medical Imaging
Background:
- Stroke is a leading cause of death and disability worldwide.
- Atrial fibrillation (AF) is a primary mechanism for cardioembolic ischemic stroke.
- Left ventricular hypertrophy (LVH) is associated with a doubled stroke risk.
Purpose of the Study:
- To investigate the association between LVH and stroke risk.
- To explore the relationship between AF, LVH, and ischemic stroke.
- To examine the link between LVH, carotid stenosis, and ischemic stroke.
Main Methods:
- 256 stroke patients from Sibiu County Clinical Emergency Hospital were studied.
- Echocardiography and carotid Duplex ultrasonography were used for examination.
- Patients were categorized based on AF presence, LVH, and carotid stenosis severity.
Main Results:
- LVH was identified as a significant contributing factor to ischemic stroke.
- The association was particularly strong in patients with carotid stenosis > 50%.
Conclusions:
- LVH plays a crucial role in ischemic stroke development.
- The presence of both LVH and significant carotid stenosis (>50%) elevates stroke risk considerably.
Abstract:
Stroke represents the third - leading cause of death after heart and neoplastic is ease and is one of the biggest cause of disability worldwide. Cardioembolism, through its principal mechanism - atrial fibrillation - constitute an important cause of ischemic stroke. Otherwise, left ventricular hypertrophy (LVH) has been associated with a twofold increase in stroke risk. The study aims at highlighting significant associations between several risk factors of stroke -LVH and atrial fibrillation (AF), respectively LVH and cardiac stenosis contributeng to ischemic stroke. The study comprised of 256 patients with stroke, hospitalized in the County Clinical Emergency Hospital, Sibiu, Romania; they were examined by ultrasound by echocardiography and carotid Duplex echography. The patients were divided in subgroups that were later compared to one another: 167 patients had atrial fibrillation (group A), 89 patients did not have atrial fibrillation (group B). Then both groups were divided in 2 subgroups (with or without LVH). It has been identified another two groups (66 patients with carotid stenosis <50%) and 116 patients with carotid stenosis >50% and each group was divided in 2 subgroups (with or without LVH). LVH is an important contributing factor in ischemic stroke in patients also presenting carotid stenosis > 50%.
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