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Dynamic Light Scattering Analysis for the Determination of the Particle Size of Iron-Carbohydrate Complexes
Published on: July 7, 2023
Estimation of the molecular weight of nanoparticles using a single small-angle X-ray scattering measurement on a
Alexander Zhigunov1, Josef Pleštil2
1Institute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, 162 06, Prague 6, Czech Republic. zhigunov@imc.cas.cz.
Abstract:
Both small-angle scattering methods, X-rays (SAXS) and neutrons (SANS) rank among the methods that facilitate the determination of the molar mass of nanoparticles. Using this measure, aggregation or degradation processes are easy to follow. Mono- and multichain assemblies of nanoparticles in solution could be resolved, swelling ratio can also be obtained. In this work, we present a method that allows extraction of additional information, including molecular weight, from a single scattering curve, even on a relative scale. The underlying theory and step-by-step procedure are described.
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