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Related Concept Videos

Stress and Mental Health01:30

Stress and Mental Health

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Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
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Flashbulb Memory01:16

Flashbulb Memory

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A flashbulb memory is a highly vivid and detailed memory, often linked to events of significant emotional impact. These memories stand out in contrast to everyday memories due to their clarity and the precision with which they are recalled. The strong emotions associated with the event act as a catalyst, ensuring that specific details, such as one's location, actions, and even peripheral elements, are etched into memory with remarkable accuracy. For example, many people can vividly recall...
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Dimensions of Health and Illness01:21

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The factors influencing the health-illness continuum can be internal or external and may or may not be under conscious control. They are related to the following eight human dimensions, and each dimension is interrelated to one other.
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Psychological Responses to Stress01:20

Psychological Responses to Stress

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Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
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Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

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Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
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Stress01:20

Stress

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When a force is applied on a body, it undergoes deformation. In order to restore the body to its original shape and/or size, an opposite or restoring force is generated within the body. This restoring force is equal to the magnitude of the applied force, but acts in the opposite direction. The amount of this restoring force developed per unit area of the body is called stress. Stress is a tensor quantity and has the SI unit pascal. Stress can be separated into four broad categories depending...
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Related Experiment Video

Updated: Nov 9, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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Highlights from a year in a pandemic.

Miriam Merad1, Nicolas Vabret1

  • 1Precision Immunology Institute, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY.

The Journal of Experimental Medicine
|April 9, 2021
PubMed
Summary

The COVID-19 pandemic revealed global healthcare system vulnerabilities. A year of this global health crisis spurred scientific advances and altered scientific communication.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Epidemiology

Background:

  • The COVID-19 pandemic represents a significant global health crisis, highlighting systemic weaknesses in healthcare infrastructure worldwide.
  • Understanding the multifaceted impact of this novel coronavirus disease (COVID-19) is crucial for future pandemic preparedness.

Purpose of the Study:

  • To reflect on the key lessons learned during the first year of the COVID-19 pandemic.
  • To analyze scientific progress in understanding COVID-19 and evaluate strategies to control its spread.
  • To examine the influence of the pandemic on global scientific discourse and collaboration.

Main Methods:

  • A retrospective analysis of the first year of the COVID-19 pandemic.
  • Review of scientific literature and public health reports.

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  • Discussion of scientific advancements, intervention strategies, and their impact on scientific communication.

    • Main Results:

    • Significant scientific breakthroughs in understanding SARS-CoV-2 virology, transmission, and pathogenesis.
    • Varied success in implementing public health interventions to curb viral spread.
    • Observable shifts in scientific publishing, data sharing, and global research collaboration.

    Conclusions:

    • The COVID-19 pandemic underscored the need for robust, adaptable healthcare systems and rapid scientific response.
    • Effective pandemic control requires a combination of scientific innovation and coordinated global public health strategies.
    • The pandemic has reshaped scientific communication, emphasizing open science and international cooperation.