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Recurrent anti-NMDAR encephalitis during pregnancy combined with two antibodies positive

Hong Liu1, Xiu Chen2

  • 1Department of Neurology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.

Archives of Women'S Mental Health
|April 9, 2021
PubMed

Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune synaptic encephalitis likely mediated by neuronal surface antibody. Clinically, it is characterized by a variety of neurological and psychiatric symptoms, predominantly affecting young women. Recurrent anti-NMDAR cases combined with double-antibody positive during pregnancy have not been reported. We report a 19-year-old pregnant woman with recurrent anti-NMDAR encephalitis and double-antibody positive. Through our case report and a review of the literature, we hope to heighten an awareness of anti-NMDAR encephalitis, particularly in a pregnant setting.

Keywords:
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitisDouble-antibody positivePregnancyRecurrent

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